Comparing Sildenafil, Tadalafil, and Vardenafil
Sexual activity is an important indicator of men’s health. Any dysfunctions and disorders are perceived by men extremely difficult and sometimes critically, therefore doctors advise to undergo examination and choose drugs to maintain sexual health. And due to the wide variety of sexual stimulants, it is difficult for men to decide which is better to choose.
The choice should clearly be based on the prescription of the attending physician, as well as on the composition, the principle of action of the drug. Earlier all sexual dysfunctions were treated with sildenafil (Viagra). Today the pharmaceutical industry has many offers — vardenafil (Levitra) and tadalafil (Cialis).
Features of drugs for ED treatment
Viagra is the most popular and world-famous drug for improving potency and erection. Today, experts have created many new drugs that can be a worthy alternative to the expensive and not always available Viagra. All stimulants of erectile function can be divided into several groups:
- synthetic drugs with rapid and strong effects, for example, Viagra, Levitra and Cialis;
- homeopathic preparations containing natural components sexual stimulants;
- biologically active additives to maintain sexual health with plant and animal components in the composition.
There are also many drugs in the form of vitamin-mineral complexes, the composition of which saturates the body with all the useful resources for the full work of the whole body and reproductive system.
The most popular ED drugs are synthetic stimulants since they give a strong and stable effect. Dietary supplements and homeopathic medicines are more often used to prevent problems of this kind.
Levitra vs Cialis vs Viagra: Comparison of ED drugs
So, Viagra, Cialis and Levitra are considered the best remedies for potency and erection. The primary differences can be identified by several indicators – the mechanism of action, composition, method of application, indications and contraindications and other important criteria.
Active ingredients
The first thing you need to know when choosing a drug for potency – a variety of active components. Indications and contraindications, as well as the principle of the drug and its effectiveness, directly depend on the main constituent substance. The active ingredients of these drugs are the following components:
- Viagra – contains sildenafil citrate, which inhibits PDE-5 and releases nitric oxide, helping a man achieve an erection. The action of the substance occurs 30-60 minutes after taking the pill and lasts 3-4 hours;
- Levitra – contains vardenafil, which is also a type 5 phosphodiesterase inhibitor. After taking the pill, vardenafil begins to act faster than sildenafil or tadalafil, maintaining the effect for about 10 hours;
- Cialis is a last-generation drug that contains tadalafil, which begins to act 15-20 minutes after taking the pill and can maintain the effect up to 36 hours.
Indications
Regardless of whether it is a natural or synthetic cure for impotence, experts insist that it is necessary to take such drugs taking into account indications and contraindications. Significant reasons for taking tablets and capsules are the following phenomena:
- decreased libido and sexual desire for the opposite sex;
- weak and unstable erection;
- erectile dysfunction;
- premature ejaculation and inability to have long sexual intercourse;
- the insufficient size of the penis during arousal;
- lack of spontaneous and morning erections;
- small quantity and low quality of ejaculate.
Any sexual disorders of physiological or psychogenic etiology need timely treatment. Only a medical specialist can select drugs based on data from a comprehensive diagnosis of the patient.
Mechanism of action and duration
To determine which drug is the best among the presented leaders according to the demand and recommendations of specialists, it is also important to compare their principle of action and its duration. Namely:
- Viagra – the effect occurs an hour after taking the pill and lasts about 3-4 hours;
- Levitra – the effect occurs 15-20 minutes after taking the pill and lasts 8-10 hours;
- Cialis – the effect of the drug occurs 15-30 after taking the pill and can last about 36 hours.
The mechanism of action of all these synthetic components is as follows:
- expansion of veins and narrowing of arteries to quickly achieve an erection and prolong the state of arousal;
- the release of nitric oxide, which is responsible for the duration and hardness of an erection;
- acceleration of blood circulation in the pelvic organs, which improves the quality of an erection and also increases the sensitivity of erogenous zones, thereby increasing libido.
Both Levitra, Cialis and Viagra prolong the effect of nitric oxide molecules, increasing blood flow to the external genital organs. The difference in their action is in the duration of the effect, in addition, each organism differently perceives one or another component in the composition of the tablets.
Important: All three drugs will work only during sexual stimulation.
Dosage
All these drugs should be taken shortly before sexual intercourse, namely:
- Viagra – the recommended dose is 50 mg taken 1-2 hours before sexual intercourse;
- Cialis – the recommended dose is 20 mg taken 30-40 minutes before sexual intercourse;
- Levitra – the recommended dose is 10 mg taken 30-60 minutes before sexual intercourse.
Sildenafil and vardenafil are not used every day but only as needed, while tadalafil can be taken daily (in the smallest dose).
Efficiency
Cialis is the most potent drug in terms of duration of action. It is an innovative drug of the latest generation. Levitra has good quality indicators and minimal risks of side effects. The third place is taken by Viagra.
Side effects
Only natural remedies are completely safe and have no side effects.
Specialists give the second place to Levitra, it is less toxic than Viagra and has fewer contraindications. If we compare the preparations of Viagra and Cialis, statistics say that the first option is much less likely to cause the negative effects of taking the pills. This leads to a high cost of Viagra.
Price
The branded Viagra costs around $30 per tablet. The price of Levitra is about $20 per tablet, and Cialis – $15 per tablet.
Knowing how expensive branded drugs are, many people prefer to buy generic medications with the same active ingredients. For example, Texas Chemist offers a fixed price for all these remedies: only $2.08 per tablet.
Which drug to choose?
According to their characteristics, these drugs are quite different. Their features should be taken into account when changing or selecting a treatment. Sildenafil and vardenafil have the same half-life and duration of effect. Tadalafil begins to work a little later but its effect lasts much longer.
Most PDE-5 inhibitors are excreted in high need. The long duration of Cialis makes it possible to take fewer pills and freely engage in casual sex. In the table below, we summarized all the differences between the ED drugs:
Viagra | Cialis | Levitra | |
Active ingredient | Sildenafil | Tadalafil | Vardenafil |
Recommended dosage | 100 mg | 20 mg | 20 mg |
Max. daily dosage | 200 mg | 40 mg | 40 mg |
Effect | Strong erection | Strong and lasting erection | Strong erection |
Duration of action | 4-6 hours | 36 hours | 10 hours |
Onset of action | 40-55 minutes | 15-20 minutes | 30-45 minutes |
Compatibility with alcohol | No | No | No |
Side effects | Runny nose, redness of the skin, nasal congestion (7% of cases) | Not observed in 98% of cases | Not observed in 97% of cases |
Addiction | No | No | No |
Effect on the hormonal level of the body | No | No | No |
Price in a regular city pharmacy (brand) | $30 | $20 | $15 |
Price in Texas Chemist | $2.08 | $2.08 | $2.08 |
Conclusion | The first and proven drug to increase erection | It is popular due to its long-lasting effect and the absence of side effects | The golden mean in terms of duration; has no side effects |